As a means to noninvasively assess concentrations of certain small molecules in the living body, in vivo magnetic resonance spectroscopy enables the investigation of metabolic systems amidst a high degree of native biological context. Many open questions, however, remain to be explored regarding the methodological limits and appropriate clinical and research application of this tool.


BMENE 4490. Magnetic Resonance Spectroscopy: A Window to the Living Brain

Magnetic resonance spectroscopy (MRS) allows the detection and quantification of chemical compounds from localized regions in living tissue, e.g., the brain, in a noninvasive fashion. It thereby provides a powerful tool to assess key aspects of brain metabolism and function. The repertoire of measurable compounds along with the quantitative character of the derived information makes MRS a versatile tool for the identification of clinical conditions, for longitudinal patient monitoring and for treatment control and monitoring of virtually all disorders with a metabolic signature. This educational course comprises all aspects of in vivo MRS from theory to experiment, from data acquisition to the derivation of metabolic signatures, and from study design to clinical interpretation. Anyone interested in gaining an understanding of MRS techniques, their potential and the limitations of their application in vivo will find this course useful.

The course bridges the gap between theoretical concepts, hands-on training in MRS data literacy and direct experimental experience on a human 3T MR scanner. This 13-session combined academic course and “boot-camp” will provide novices in MRS the requisite know-how for future engagement in MRS research and diagnostics.

Interested in joining BMENE4490?

Gain access to course lectures, office hours, practical sessions, and other materials by requesting to register below. 



    Collaboratory In Vivo MR Spectroscopy Journal Club

    Is taking a course not enough spectroscopy for you? Join the Collaboratory In Vivo MR Spectroscopy Journal Club! In this monthly journal club, with support from the Collaboratory at Columbia University, we present impactful, especially well-constructed, or otherwise compelling works within and around the field of in vivo magnetic resonance spectroscopy among a diverse group of researchers involved to various degrees and from various angles of attack in this specialized but growing domain of inquiry.


    Interested in joining the Collaboratory In Vivo MR Spectroscopy Journal Club?

    Gain access to our editable presentation scheduling document as well as join our mailing list by either emailing us directly or filling out the below contact form. 


      Interested in speaking at the Collaboratory In Vivo MR Spectroscopy Journal Club?

      Register as a speaker by either emailing us directly or by filling out the below contact form.